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A Soyuz capsule carrying two Russians and an American on Thursday successfully docked with the International Space Station, after a two-day journey, TASS news agency quoted the mission control centre as saying.
The TMA-21 capsule docked automatically at 2309 GMT Wednesday, the centre that is close to Moscow said.
The three astronauts blasted off for the ISS on Tuesday in a spaceship named after the first man in space Yuri Gagarin in honour of his historic flight 50 years ago.
Cosmonauts Alexander Samokutyaev and Andrei Borisenko are making their first space flight while US astronaut Ronald Garan is making his second mission, having already flown on the US shuttle Discovery in 2008.