Spaniards discover link between cancer genes
26 January 2006, MADRID — A Spanish scientific team has solved a 25-year mystery concerning the genes which cause cancer.
26 January 2006
MADRID — A Spanish scientific team has solved a 25-year mystery concerning the genes which cause cancer.
Maria Dominguez, who leads the team at the Neurosciences Institute in Alicante, has found two new genes which cause and spread cancer.
In an article in the respected British science journal Nature published on Thursday, her team's findings were reported – the first time in 20 years a solely Spanish study has achieved this.
Sine 1980, scientists have catalogued about 200 genes related to cancer.
So far genes they have been classified into oncogenes, which stimulate the division of cells and which lead to tumour growth, and tumour-suppressor genes which restrain cell growth.
When the latter are missing or deactivated by a mutation, they allow cells to grow and divide uncontrollably, typically with breast and ovarian cancer.
The oncogene starts the division process of the mutated cell, but the cancer does not take hold until the suppressor genes are deactivated.
Dominguez and her team discovered was the link between these categories – genes now known as Pipsqueak and Lola.
The team used insects to make the discovery.
[Copyright EFE with Expatica]
Subject: Spanish news